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In the presence of glucose, they are strongly repressed, while in nonfermentable carbon sources, they show a basal level of expression and are poised for induction by galactose.
Similar(59)
However, in the basal state, ELK4 is already bound to target genes poised for zymosan induction.
H3.3 is incorporated into promoters of developmentally regulated genes, and these loci bear both H3K27me3 and H3K4me3 marks, marking these promoters as "bivalent domains" poised for transcriptional induction (Bernstein et al. 2006; Goldberg et al. 2010; Banaszynski et al. 2013).
In this way, the A20 promoter is poised for rapid transcriptional induction when NF-κB is activated.
The peculiar chromatin signature of bivalent domains renders the respective developmental genes poised for activation, so that induction of transcription upon differentiation stimuli can occur extremely rapidly.
But poised for what?
Zambia seemed poised for recovery.
He is poised for a breakthrough.
Vehicles and machines are poised for action.
Bono seems poised for more tech success.
"We are poised for progress," he said.
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CEO of Professional Science Editing for Scientists @ prosciediting.com