Sentence examples for poised for binding from inspiring English sources

The other chromodomain in each dimer is poised for binding H3 K9me3 in a neighboring nucleosome to facilitate spreading of Swi6 across chromatin.

In line with previous findings which determined an important role of H2A.Z in the regulation of transcription [ 104– 106], our results suggest that H2A.Z-marked promoters are poised for increased TF binding (Additional file 1: Figure S4).

This overview recounts the background to the development of a microarray system that is poised for surveying proteomes for carbohydrate-binding activities and glycomes for assigning the oligosaccharide ligands.

Docking studies show a snug fit for DCoA in the acceptor substrate binding site, well poised for a nucleophilic attack on the ATP γ-phosphate, its interaction being stabilized by a total of 89 contacts (Table 2).

Although activity-based screens generally have not identified substrate phosphorylation site inhibitors, binding assays appear better poised for success.

Genes could come under Hairy control by the acquisition of activator binding to regions already poised for Hairy repression (although they offer no evidence for this claim).

Thus, the structure represents a non-cleavable conformation of the repressor, but one that is poised for cleavage after modest rearrangements that are presumably stabilized by binding to RecA.

We propose that CTCF binding maintains rDNA repeats in a state poised for activation.

The hydrolytic centre is situated on the cytoplasmic side of the protein with conserved aspartates and lysines lining the binding pocket and coordinating the binding of Mg2+, IDP and a water molecule that is poised for nucleophilic attack12.

Such genes may represent loci that are poised for capture in the Hairy regulatory network through stepwise acquisition of activator binding sites.

This is consistent with a secondary binding site for RS2 that becomes engaged while RS1 is poised for phosphorylation in the active site of SRPK1.