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Single points skin sutures were performed with Nylon 2-0 or 3-0 (Shalon®, Shalon Fios Círurgicas Ltda).
Translational biomarker data were correlated with efficacy (time-to-treatment failure and OS) and safety study end points (skin rash) using univariate analyses.
At the indicated time points, skin samples were taken for the purposes of immunohistochemical staining and microscopy, immune infiltrate extraction and flow cytometric analysis, and/or RNA expression studies (see Supplementary Materials and methods).
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Billed as a true story of love, betrayal and reconciliation, the working title gets to the point: Skin.
Key point: Skin biopsy is only recommended when skin lesions last longer than 24 h.
Moxibustion significantly increased the SP6 point skin surface temperature, with a peak increase of 11°C at 4 min (p <0.001).
Body fat percentage was determined by a seven-point skin-fold measurement using a calibrated calliper (GPM, Zurich, Switzerland).
"A human look is much more than the movement of hundreds of points of skin on the face," Dr. Neumann said.
By using charts of specific points of skin and tissue thickness, scientists can produce a relatively unique face that can then be used to help identify the decedent.
The points and skin incisions basically followed Millard's principle with addition of a small triangular flap in the lateral lip segment for unilateral complete cleft of the primary palate.
Clinical end points were skin toxicity, clinical response, time to progression (TTP) and overall survival (OS).
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