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According to the biogenesis model of ta-siRNAs, the miRNA cleavage sites on the target transcripts could define the start points of the phased sRNA sets (Allen et al. 2005; Williams et al. 2005).
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Numbers attached to some points of the phase space trajectory refer to index i of the original contour line.
Transitivity gives the probability that two points of the phase space trajectory neighbouring a third are also directly connected.
Details are given in [3 5, 19] or [20]: Clustering coefficient gives the degree to which points of the phase space trajectory tend to cluster.
Finally, R is a l × l square and symmetric matrix that can be displayed as a false colour heat map representing the distances between all points of the phase space trajectory according to the used norm (Fig. 1).
These curves define the points of the phase space where Y and Z do not change.
The primary end points of the phase II portion of the study were objective response rate and safety of this combined treatment modality at the RD level.
This report summarises the effect of axitinib vs sorafenib on patient-reported kidney cancer-specific symptoms/functioning and health status, which were secondary end points of the phase III study.
For example, prospectively assessed QOL (even after completion of protocol treatment) was proposed and performed as one of the secondary end points of the phase III trial of combined therapy of Docetaxel plus Cisplatin and Fluorouracil for advanced gastric or gastroesophageal adenocarcinoma [ 10].
Each point of the phase-space diagram (H, Kz) refers to a torus.
The research addresses current questions of strong-interaction physics as confinement in normal nuclear matter, chiral symmetry restoration in deconfined matter at high temperatures and densities, and the search for the critical end-point of the phase boundary.
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