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To prioritize alterations for functional study, we used two points of rationale: A) Because the phenotype in question is structural genomic rearrangements, genomic deletions (such as CHD1 and MAP3K7) could be causative or consequences of this phenotype, since they result from structural rearrangements.
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We thank the reviewer for pointing out this miscommunication of rationale.
This chapter attempts to share with the readers, from a clinical point of view, the rationale of footwear design in relation to common foot problems.
From a clinical point of view, the rationale behind the functional module analysis and biomarker discovery performed by atBioNet is to find effective and robust biomarkers for a disease.
Specific points like the rationale of using HIV-1 regulatory genes instead of structural genes, the possibility of using multiple injections of vaccine candidates or the importance of pre-existing immunity will be emphasized, together with the risks of inducing the emergence of new HIV-1 variants upon vaccine treatment of chronically infected HIV-1 patients.
Ryan's rationale at the level of principle is sound.
Accumulated evidence points to the rationale for combination of molecule-targeted therapies to delay or overcome the acquired treatment resistance.
The rationale implicit in our ordinary concept is that an object is wholly present at all the temporal points of its existence.
These points provide a rationale for early and aggressive management of cardiovascular risk in patients with diabetes.
The main point of criticism on this rationale lies on the fact that it does not suffice to equip teachers with adequate knowledge to naturally synthesize their technology skills with teaching methods and their knowledge of their subject matter (Angeli & Valanides, 2005; Jang, 2008; Koehler, Mishra, & Yahya, 2007; Wilson, 2003).
From a rationale point of view, the utility of the system -for now- is to determine which are the diagnostic processes followed by the physicians, since the data were cross-sectional and the diagnoses were made by doctors during visits.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com