The number of expressed sequences was significantly different between T2 and all other time points at a significance level of 1%, and between T1 and T4 at a significance level of 5% (McNemar test).
These values were significantly different, except for week 24, from pre-stroke values, or from values of the healthy (left) hemisphere for all time points, at a significance level of p<0.05.
One-way analysis of variance (ANOVA) was performed on each cohort followed by a Bonferroni post test to compare all pairs of time points at a significance level of alpha = 0.5 (95% confidence intervals).
To find a difference of 1.5 points at a significance level of 0.05 and with a power of 80% and assuming a SD of 4 points as observed in our study, investigators need to enroll 112 patients in each group.
Stepwise logistic regression was performed, with the variables associated with the end-point at a significance level of 20% remaining in the model.
The optimal predictor comprised of five genes, differentially expressed between patients who had progressed within 8 months and those who remained progression free at that time point, at a significance level of 0.00005 (random variance t-test).
The procedure was then repeated with these variables for a significance level of 5%, and a final regression was then performed to determine the adjusted risk of SMM/NM for each one of the variables significantly associated with the end-point at a significance level of 5%.
a Based on estimated completion rate of 75% b Power to detect difference of 1.67 RDQ points at 1% significance level c Power to detect difference of 1.67 RDQ points at 5% significance level Allowing for one third loss to follow up at one year we sought to recruit 1,350 participants.
Urine acetaminophen mercapturate concentrations were higher at all time points, however, significance was only reached at 4 h post-acetaminophen dose (P = 0.019) after 4 weeks of SBR supplementation when compared to week 0.
The CP system displayed a 'point-contact' configuration along the interface with high pressures recorded at these points, the significance of which is unknown.
