Reviewer 1 points out an issue with the reliability of WNT/beta catenin reporters in detecting WNT signaling and that they should not be considered definitive.
This again implies that most of the change occurs around the cut-points-an issue raised by Van Den Hout and Matthews who split cognition into two groups based around a cut-point between 21 and 22 for a two-state illness-death multi-state model [ 16].
It avoids conflicts between concurrently simulated grid points, an important issue in high-resolution and efficient simulations.
Our study might point to an issue that is much broader and to another conceptual level that the behavioural models cited above.
He is attempting to point out an issue which the photo below questions.
Instead, I'll point to an issue that the South just tackled: the Confederate flag.
Half of the comments pointed to an issue with too much assertiveness and the other half described too little.
Put together, these results point to an issue of confounding rather than moderate or severe multicollinearity.
This last point raises an issue in which we might expect to see future developments.
However, our results in addition to similar work regarding ATM [ 7, 71] point toward an issue under the second criterion.
