One caveat that should be pointed out in this model is that our transgene is likely expressed principally in stromal cells, since it was previously shown that deletion of the 3'-region of the human TNFα gene resulted in the loss of macrophage-specific TNFα expression [ 16].
But, as pointed out in [13], detailed switch model of MMC costs excessively long simulation time.
However, in this newly identified signaling pathway, some outstanding questions have to be addressed as pointed out in our current working model (Fig. 4).
As it was pointed out in the third part, in model (17), the decision variables of the model are x and y.
As Sarah Jeong pointed out in Forbes, the model statute provided by Citron in her upcoming book, Hate Crimes in Cyberspace, explicitly excludes "disclosures that related to the public interest".
To avoid the expensive MC simulations required for spatially detailed models of the sarcomere, various ODE models describing the average behavior of the regulatory unit have been reported, 13, 15, 20, 21 but the problems and difficulties in the construction of such a mean field ODE model were pointed out in the literature.
The results shows that the stability region is not only determined by the parameters of the system configuration and the bidding adjustment-as pointed out in conventional model, but also by the player's imperfect knowledge about the market.
Future work is pointed out in applying the present model and framework, defining efficient ways of evaluating individual tailoring components, and improving effectiveness through the creation of accurate and complete user- and context models.
The local and even global phenomena observed in the model (6)–(7) have been pointed out in single cell models [29], [30], [83], [84].
The complexity of both models is pointed out in SISO models as well as in MISO ones.
