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Several findings have pointed a role for both ionotropic (Croucher et al. 1995) and metabotropic (Wong et al. 1999) glutamate receptors in promoting seizure activity in various animal models of epilepsy.
The candidate gene studies based on single genes have pointed a role for genes involved in, e.g., GH/insulin/IGF-1 signaling, immune regulation, and lipoprotein metabolism (Supporting Information Table S1), although most of these results have not (yet) been confirmed in sufficient independent studies.
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Epidemiological and clinical studies point a role for negative experiences in the early life as risk factors for the development of psychopathologies in adulthood.
A number of studies have pointed towards a role of PRL in breast cancer development.
Previous studies pointed to a role of activated γδ T cells in BD [ 17, 31, 46].
Previous studies already pointed towards a role for viruses in development human T1DM.
Recent evidence has pointed towards a role of hemoglobinopathies in interfering with cytoadhesion.
Recent studies also pointed to a role for Notch signaling in human breast cancer.
Previous studies have pointed to a role for mDia2 in mammalian filopodia.
More site-directed mutations pointed to a role for Y169 in kinetics and binding [ 37].
Previous studies have systematically pointed to a role of metabolic enzymes in cognitive ability.
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CEO of Professional Science Editing for Scientists @ prosciediting.com