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The primary effectiveness end point will be evaluated for non-inferiority, with a nested test of superiority, based on the proportion of responders (defined as alive, free from HF-related events, with improvements in New York Heart Association class or improvement in Kansas City Cardiomyopathy Questionnaire quality of life score) at 12 months.
The primary efficacy end point will be evaluated by blinded investigators.
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In this paper one of the data points will be evaluated and compared to the prediction models.
The following co-primary end points will be evaluated on postoperative day 7: total oral and enteral caloric intake, abdominal distension and abdominal pain.
Primary and secondary end-points will be evaluated using the same procedure for all eligible cancer deaths, in the baseline and in the effectiveness assessment.
The following primary end points will be evaluated at postoperative day (POD) 7: Total oral or enteral caloric intake; Abdominal distension determined using numeric rating scales (NRS); Abdominal pain determined using NRS.
Primary and secondary end-points will be evaluated for all eligible cancer deaths as follows: 1. Identification of eligible cancer deaths from the ward: the cancer deaths in the ward will be identified through the hospital's deaths documentation (which lists all deaths regardless of cause).
Evelyn Erskine, a spokeswoman for the Bloomberg administration, said in an e-mail that the board's program, which she referred to as a "pilot program," would receive money until the new calendar year, "at which point it will be evaluated".
The uncertainty associated with the point estimates will be evaluated using bootstrapping [ 35].
The genotype frequency of ITPKC and CASP3 SNPs will be summarised by proportions and percentage, and the association between the primary end point and SNPs will be evaluated by a logistic regression model.
Costs and outcomes will be reported separately at each time point and trends over time will be evaluated.
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