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Substudies of cardiovascular end point trials and mechanistic studies should be methodologically sound and designed to test specific models.
The 3 regressors used in the previous analysis remained unchanged; that is, one for the safe response (i.e., +20 point trials) and 2 for receiving the punishment feedback (i.e., −40 and −80 point trials).
Ongoing clinical end point trials will provide further insight into the role of n-3FA supplements in CV prevention (24).
There were a total of 5 regressors classified as follows: one for making a safe response (i.e., +20 point trials); 2 for making a risky response (i.e., +40 and +80 point trials); and 2 for receiving punishment feedback (i.e., −40 and −80 point trials).
60– 63 Recent clinical end point trials indicate that aliskiren might also have end organ protective effects similar to ACE-I and ARBs in high risk patients.
Clinical CV end point trials conducted prior to ORIGIN also fail to provide clear answers regarding the impact of exogenous insulin on CV events.
Similar(53)
In preparation for a multinational randomized clinical end point trial of interleukin-2 in HIV-infected patients, four phase II "Vanguard" studies were initiated.
This was a prospective, randomized, open-label, blinded end point trial.
The JPAD trial was a multicenter, prospective, randomized, open-label, blinded, end point trial conducted at 163 institutions throughout Japan.
The significance of the findings in our report, however, requires further investigation in a clinical end point trial.
This trial is a phase III, multicentre, randomised, open-label, blinded-end point trial that evaluates the efficacy and safety of IVIG+CsA therapy.
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