Sentence examples for point to constraints from inspiring English sources

3 4 They also point to constraints in determining societal valuation of orphan treatments given practical difficulties in obtaining accurate cost effectiveness information among small patient populations, 3 5 and to the fact that low prevalence of disease is likely to mean low budgetary impact.

The use of synthetic promoters has pointed to constraints on the orientation and spacing of ABRE and the CEs [ 18], albeit results from transient expression experiments may not fully reflect in planta distance and orientation requirements of ABA-responsive genes.

Comparisons between species demonstrate that non-coding sequences rapidly lose structural homology over time, although isolated sections of highly conserved sequence may point to functional constraints on IGS divergence; the first conserved domain described for chromosome 33 above contains a Leishmania RNA-binding site GGATC [ 2].

Finally, the measurements were taken on only one day per assessment point, due to constraints inherent with pilot studies and natural experiments.

We used the fact that all the candidate models can be considered to be models with five change points, subject to constraints.

Interface element including point-to-surface constraints for three-dimensional problems with damage propagation.

Travel surveys like the ones performed in more advanced countries can be a starting point to identify the constraints faced by low-income commuters (affordability, accessibility, etc).

These data point to structural RNA constraints on Lin28a's interaction with its targets.

In this paper we present a methodology for the design of a feedforward control law to be applied to a closed-loop PID-based control system for a multi-input multi-output process in order to achieve a minimum-time rest-to-rest transition of the system from an equilibrium point to another subject to constraints on both the control and process variables.

She also pointed to the constraints on vaccine supplies this past fall as part of the CDC's reasoning behind its recommendation to focus on high-risk groups.

The majority of key informants pointed to resource constraints in nursing education institutions, particularly the lack of budgets, teaching infrastructure, student accommodation, and teaching equipment.