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Not surprisingly, there are very few Japanese startups, and existing Japanese companies tend to be risk-averse to the point of ossification.
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From a histopathologic point of view, enchondral ossification contributes to bone formation in the spinal ligaments [ 16].
From an evolutionary point of view, endochondral ossification is the younger of the 2 types of bone formation (the older dermal bone was formed by intramembranous osssification).
The first time point of detection was ED14.5, when the centres of ossification initiate in the mouse front limbs.
These samples became more mature with prolonged in vivo implantation, and few signs of ossification were observed at all time points except for one sample that had not been wrapped completely.
For example, peak stimuli at the mid-diaphysis before the onset of ossification spread proximally and distally ahead of the ossification front.
These results confirm that, periosteoma soft tissue has the same pattern of early stage of osteoma ossification, and could be a model of ossification for further studies.
The mode of ossification of the long bones is characteristic.
Centres of ossification sometimes develop in nonbony connective tissue.
Plain radiographs and CT may show various phases of ossification: amorphous calcification, immature and mature ossification.
Concerns remain on the type of ossification occurring during callotasis.
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