The use of biochemical recurrence as surrogate end-point of aggressive prostate cancer has limitations.
For Oozing Wound, part of the point of making aggressive music is to be different, and the first step towards achieving that is to mess around with song structures.
As with the combined gene models, a score lower than the cut point is indicative of aggressive disease.
Our results suggest that 3-year PFS should be further explored as a candidate surrogate end point in RCTs of aggressive NHL using individual patient data.
Kolia is at the centre of a perfect storm of poisoned destiny, at the focal point of smart lawyers, aggressive politicians and arrogant priests.
Another point of departure: the aggressive sounds of early hardcore, that strand of amphetamine-fueled dance music that came out the UK in the 80s and reached its frenetic peak in the late 90s.
Given the relationship between anxiety, postoperative pain, and duration of hospital stay that we have identified here (not least from an economic point of view), more aggressive steps should be taken to prevent patients' postoperative troubles.
A number of different surrogate end-points for aggressive PC have been used in the studies like presence of perineural invasion [ 20], Gleason grade [ 20, 21], extra prostatic growth [ 16] and risk of recurrence [ 22].
