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My final point is regarding research and development of new drugs.
A second extremely important point is regarding the authors response to my comment #3 (Reviewer #2).
5) A point is regarding the relevance of the conclusions the authors make on the existence of cell-based limitations that preclude amyloid resolubilization in vivo to disease conditions.
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In our GPU-based reconstruction process, each sampling point is regarded as an independent seed and expands simultaneously until all surrounding patches overlap each other.
If g x, y) > t, this point is regarded as an edge point.
The inflection point is regarded as the feature points that the crack begin to propagate in Fig. 7.
When rho of ({vec {psi }_{g}}) stays no more than the given threshold rho_thr, this point is regarded as an inlier, otherwise an outlier.
The point at which the two straight lines intersect is the discontinuity in adhesion force measurement, and the discontinuity point is regarded as the T g of normal thin polymer film, which is reported in previous study [5, 25 27].
If the slip-deficit rate is larger than half of the relative plate motion, the grid point is regarded as a "slip-deficient grid"; otherwise, it is a "sufficiently slipping grid".
The weakest point was regarding promotion of employment and entrepreneurship.
Monthly changes of less than two-tenths of a point are regarded as statistically insignificant, however, and there has been no appreciable change in the unemployment rate for a year and a half.
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