Because some components of the VM are time bound (e.g. improvement of efficacy over existing intervention at a point in time), the value estimate will change over the life cycle of the intervention as new interventions are made available.
Mínguez et al. (2013) [1] proposed a method, (a) to characterize and to combine graphically both the point-in-time and extreme-value probability distribution, (b) to apply Monte Carlo simulation technique to reproduce both regimes, and (3) to use their distributions in the frame of first order reliability methods (FORM).
This paper proposes a Monte Carlo simulation technique, which allows the generation of possible outcomes for agents holding the following conditions: (i) both the point-in-time and the extreme value distributions are appropriately reproduced within the simulation procedure, and (ii) it maintains the temporal dependence structure of the stochastic process.
The mean fracture surface temperature (leftlangle Theta rightrangle) is a measure of the accessed area for heat transfer at a point in time; smaller values of (leftlangle Theta rightrangle) mean more area has been accessed.
Admission glucose is only a blood glucose value of point-in-time, which cannot reflect the status of acute glucose swings.
As a blood glucose value of point-in-time, admission glucose cannot accurately show dynamic changes of blood glucose as GV and can be influenced by many random factors.
Clinical approaches relying on point-in-time analysis of vital signs or lab values are often insensitive, non-specific and late diagnostic markers of sepsis.
In contrast, blood glucose measures depict blood glucose at one point in time and this value can fluctuate hourly.
For the follow-up A1C measurement at the 6-month post-index point in time, the laboratory value was identified during the time period ±45 days to the 6-month post-index point in time, utilizing the mean of the laboratory values available during that time interval if several measures were present.
Both the persons with dementia and their spouses expressed, at different points in time, the value of the PPAP in their life.
The VTTV would be even higher if operational costs and costs due to two cancelled trains had been included.19 However, at this point in time, the recommended values for VTTV in Sweden are based on an ad hoc approach in that VTTS is multiplied by the factor 2,20 without any theoretical or empirical justification.
