To show a difference of 10 points in the developmental quotient at 24 months of age, it would have been necessary to observe 19 children infected in utero.
Taken together, these data demonstrate tight co-regulation of metabolic reprogramming and progression through meiosis, and hitherto unobserved partial mobilization of trehalose in response to specific arrest points in the developmental program.
Like Lbx1 in vertebrates, lb marks an entry point in the leg muscle developmental programme and specifies properties of myoblasts that give rise to appendicular muscles.
It is interesting that only 8% of these genes were shared by E11.5-E14.5 and E14.5-E15.5, pointong to differences in the developmental program at these times.
The lethal effect of paired box transcription factor 8−/− mutation (lack of a thyroid gland and TH) compared with the nonlethal effect of TRα/ TRβ null mutations in mice points to the developmental actions of TR isoforms in the absence of TH (3, 4).
At a certain point in developmental time, the outcome of this process (i.e., the relative size of the toes) is a result of the evolved rates of change of the toe-size variable, achieved by a scaling of the relative speed of system dynamics of the toes.
A SII figure of say 22 indicates that there is an absolute difference of 22 percentage point in developmental vulnerability from the lowest to the highest SEIFA IRSAD decile.
Individuals with shared genotypes always had the same phenotypic gender in both populations, pointing to the developmental stability of the sterility trait.
GD13 is a critical developmental point in the mouse, as it is the beginning of neurogenesis of the hippocampus (Angevine 1965; Haubensak et al. 2004), and the rat reaches this point a day or two later (Bayer 1980).
To protect against all children being steered, inadvertently, in a parental direction that proved disastrous at some later point in time, developmental processes were selected to vary children's susceptibility to rearing (and other environmental influences).
