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Point-of-departure (POD) values were defined as the concentrations at which the concentration response curve increases or decreases more than one standard deviation of the vehicle controls.
Determined POD values were generally consistent with the curve fitting and reflected increased cytotoxic effects observed after 24 and 48 h compared with early time points (30 min) (i.e., POD values for cytotoxic parameters generally decreased over time).
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All POD values are based on nominal concentrations.
The good POD value is accompanied by a very low POFD value and the relatively low FAR.
On POD 2, laboratory values were taken.
Overall, RNA-Seq POD and ED50 values were considered to be more accurate due to its ability to detect lower abundance genes and greater dynamic range.
Higher heritability estimate values were obtained for HPW, HSW, DFL and plant, pod and seed morphological traits ranged from 0.54 to 0.90 in both conditions (Table 1).
In POD the sensitivity is 0.51, specificity 0.81 and PPV 0.59; in non-POD hepatic failure the values are 0.29, 0.73 and 0.31 respectively.
Microarray and quantitative real time PCR expression values are mentioned as fold change of transcript in pods compared to different tissues.
The first step in developing toxicity values is identifying, for each data set, a point-of-departure (POD) dose, from which extrapolations to environmentally relevant doses are made.
From the normalized anomaly calculations, the POD value of models has been computed.
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