Sentence examples for pocket structure from inspiring English sources

In this paper, the multi pocket structure is regarded as a combination of Kirchhoff plates.

The newly found triterpene inhibitors might structure-dependently insert into the pocket, and the pocket structure of each enzyme might, three-dimensionally but slightly, differ among them.

Ten amino acids that have high affinity to three different regions of t-PA are identified by the amino acids location method on the basis of candidate pocket structure of t-PA.

The triterpene frames could be used for screening new inhibitors of the enzymes, and computer-simulated drug design using the frame and pocket structure may in theory be a possible approach to develop new inhibitors.

We are continuing the study related to the alteration of pocket structure of VDR by 22-alkyl substituent of ligands and the relationships between the alteration and agonistic/antagonistic activity.

It is, however, possible that a further decrease in pH, particularly in the range near the pKa of carboxylates (4 4.5) may induce substantial changes in the RKIP pocket structure and its ligand-binding properties.

Here we have applied Fourier transform infrared (FTIR) and nanosecond time-resolved optical spectroscopy to hIDO1 variants with modified heme pocket structures to identify important amino acid residues that stabilize the substrate in the active site.

Scanning electron microscopy revealed that the beads were spherical in shape with few oil filled channels distributed throughout the surfaces and small pocket structures inside the matrix confirming oil entrapment.

Furthermore, because of the similarities of the ATP pocket structures among different kinases, most of these inhibitors affect multiple tyrosine kinases and have off-target activities (D'Cruz and Uckun, 2012).

Additionally, none of the d-amino acids was recognized and hydrolyzed by mammalian orthologs, which indicates the high stereospecificity of both enzymes around the S2 binding pocket (structures in Online Resource 1).

Finally, the ligand binding kinetics, which also indicate that the ferrous tomato Hb is only partially hexacoordinated, will be discussed in relation with the heme-pocket structure.