Sentence examples for pocket function from inspiring English sources

A Ser193 might affect the oxyanion pocket function, similar to various factor XIa mutants of residue 193 with reduced activity and inhibitor binding capacity [113].

It is possible that the hydrophobic pocket functions to bind a substrate.

The pockets function for men like purses do for women, he said".

The binding pocket may function in regulation, or perhaps it serves as a second catalytic site.

Such an effect might then alter the orthosteric binding pocket or function of the GPCR heterodimer partner.

These results demonstrate the exquisite sensitivity of trabecular and conduction myocytes to pocket protein function during ventricular chamber development.

The Cip/Kip family members, p21CIP1, p27Kip1, and p57Kip2, modulate the activity of all G1/S CDK complexes, which in turn negatively regulate pocket protein function (Besson et al., 2008).

He puts the money in his shirt pocket, which functions as a floating bank; when someone needs a handout, Tobón reaches into his pocket.

The pocket telephone functions as a mobile desk phone, allowing Medical Center personnel to place and receive calls on their Stanford telephone number while away from their desk.

A more recent study showed that insertion of rimantadine into these pockets could function as "molecular wedge" that attenuates conformational breathing needed for cation flow through the N-terminal constriction of the p7 channel (Dev et al., 2015).

Thus, these novel pocket descriptors can be used to predict target druggability or to calculate similarities between binding pockets, e.g. to predict potential off-targets or to perform protein function de-orphanization.