Sentence examples for pocket altered from inspiring English sources

Second, we see a binding pocket altered in size and hydrophobicity.

Moreover, mutations in the putative NADH-binding pocket alter several aspects of Edc3 function in yeast and human cells, including subcellular localization, P-body formation, and the control of mRNA degradation.

Changing one amino acid from valine to isoleucine in the fifth transmembrane domain, which is thought to contribute to the shape of the pocket, alters the receptor protein in such a way that heptanol, instead of octanol, produces the greatest effect.

The activity of all of the mutated enzymes with non-specific substrates indicates that the substrate binding pocket is altered and has become flexible toward other substrates after mutation.

To answer this question we developed a panel of peptides designed so that amino acids interacting with the p6 and p9 predicted MHC binding pockets were altered.

A change in a single amino acid can change the form of the pocket, thus altering the chemicals that fit into the pocket.

Mylan's latest announcement – that it would offer various new pricing concessions to families on lower incomes and those who have to pay out of pocket, cannot alter this stark fact.

These results confirm and extend previous findings that locostatin can similarly bind the RKIP pocket without altering association with Raf-1 or kinases such as PKC.

Small amino acid substitutions within this alcohol binding pocket markedly alter the pharmacology of alcohol inhibition of L1 adhesion (Dou et al., 2011).

Amino acid substitutions that affect the opsin's retinal chromophore binding pocket can alter the pigment's absorbance spectrum, generating variation in spectral sensitivity [ 36, 37].

We anticipate that future work will help identify how critical somatic mutations in pocket regions alter protein function in cancer, including protein-protein interactions and drug binding.