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Furthermore, it is decided by the shorter grid period Po value for the better scattering length scale.
The Po value determined supported the in vivo feasibility of the aurone as a CNS-active compound.
PO value was determined by the Kubel method, and TH was investigated by the 2 methods: complexometric and salt settling methods (Lure 1971, 1973; Sargsyan 2014).
Finally, a clustering technique called the "k-means clustering technique" was used in identifying the pattern that exists between POs. it was found the criterion of each cluster based on the mean value could produce a great indicator in identify the different types of student in achieving the PO value, while reducing the need to carry out too much data collection and analysis.
In designing the study we set the Po value at 40% response rate.
Outlier markers were defined as those having a log10 (PO) value ≥0.
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Clusters that had Po values that were >1 SD from the corresponding population mean were rejected from these analyses.
Furthermore, the σ2/I relationship for Slo3+β4 currents shows little hint of a parabolic behavior that would imply that Po values over 0.5 are obtained.
It is important to point out that in previous studies [18] we have established that frame by frame analysis of higher signal-to-noise recordings yielded the same results as histograms (i.e. we can be confident when comparing Po values calculated using different methods).
We favor the idea of involvement of interdomain interactions between the N and C tails for the following two reasons: i) there is a body of evidence for N/C interactions as a mechanism for the regulation of Kv channel gating (e.g., [74] [79]; ii) we have previously suggested that the differences between the N termini of KCNQ2 and KCNQ3 account for their different Po values [51], [80].
Finally, patch-clamp recordings from excised patches of the PM of osteoclasts resolved small numbers of Ba2+-permeable channels with unexpectedly high Po values (0.5−0.95) in the absence of any known agonists of RyR, but that activity was massively attenuated by application of cytosolic ruthenium red or an antiserum to a cytosolic epitope of the RyR (175).
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