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Moxifloxacin is a respiratory fluoroquinolone with a community acquired pneumonia indication.
In Europe, PCV10 (Synflorix®, comprising the additional serotypes: 1, 5 and 7F) was indicated for active immunisation against IPD and acute otitis media (AOM) in infants and children from 6 weeks up to 5 years of age [ 22] and in 2013, the pneumonia indication was added.
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In patients developing nosocomial pneumonia, the indication for the drug should be evaluated within 12 hours after adequate standard care has been initiated.
It was the primary reason for intubation in approximately 17% of patients in a large international trial evaluating the characteristics of patients receiving mechanical ventilation, occurring more frequently than congestive heart failure, trauma, or pneumonia as an indication to intubate [ 2].
Bacterial pneumonia is a common indication for mechanical ventilation in the ICU.
In this prospective study, we investigated the association between presence of a virus and severity of disease in hospitalized children with severe pneumonia to provide an indication of causality.
Ceftriaxone, cefotaxime, and cefepime all have similar indications for pneumonia, skin and skin structure infections, and urinary tract infections; however only ceftriaxone and cefotaxime have an indication for the sepsis syndrome.
The BAL indication were pneumonia-induced ARDS was suspected clinically and no definite microbial was indentified from tracheal aspirate.
The majority of patients had undergone previous surgery (82 patients; mostly general surgery or neurosurgery), and were receiving the study antibiotics for intraabdominal infections (16 patients), nosocomial meningitis (11), nosocomial pneumonia (46) or other indications (27).
This discussion will confine itself to VV ECMO used in refractory respiratory failure, including clinical indications of pneumonia (bacterial, fungal, viral, aspiration), status asthmaticus, traumatic pulmonary contusions, pulmonary embolism, as well as for secondary causes such as ARDS associated with overwhelming sepsis or systemic inflammatory conditions.
As hospital-acquired pneumonia (HAP) is a frequent indication for antibiotic prescription as well as a manifestation of antibiotic resistance, antibiotic policy for HAP is an important target area for antibiotic stewardship.
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