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In summary, we have synthesized a PMO with well-defined nanorice morphology.
A periodic mesoporous organosilica (PMO) with nanorice morphology was successfully synthesized by a template assisted sol gel method using a chain-type precursor.
Periodic mesoporous organosilicas (PMO), with phenylene or biphenylene organic linkers, were thermally treated in flowing nitrogen atmosphere upon different conditions aiming the enhancement of their CO2 adsorption/separation properties.
A possible direct interaction of PMO with cellobiose, the electron donor of CDH, was tested by replacing cellobiose by lactose.
ONJ has been reported rarely in the treatment of PMO with Zol as well as with other oral and IV bisphosphonates.
Other candidate Arg-rich peptides (such as Pip peptides and B-MSP) also utilize R-Ahx-R or R-β-R (β = beta-alanyl) motifs and have been used successfully to deliver PMO with even higher activity in mdx mice (16, 17).
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Jaroniek reported PMOs with multiple bridging groups and spherical morphologies [22, 23].
This has been ascribed due to the restricted Ostwald ripening and/or migration-coalescence of the GNPs between adjacent pores of the PMOs with 1-D pore structures.
Sulfonic acid functionalised periodic mesoporous organosilicas (PrSO3H-PMOs) with tunable hydrophobicity were synthesised via a surfactant-templating route, and characterised by porosimetry, TEM, XRD, XPS, inverse gas chromatography (IGC) and ammonia pulse chemisorption.
Pip-PMO with improved cardiac exon skipping activity demonstrates highly efficient dystrophin protein expression in various muscles, resulting in up to 50% of wild-type levels of dystrophin protein in the heart in mdx mice [ 49].
When using ascorbate these activities were remarkably similar for the three glycosylated PMOs with four to five U g-1 while PMO-03328 exhibited a three-fold higher activity.
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