Limiting the amount of state support a household could receive was a "basic issue of fairness", Mr Cameron said, recalling what he said about the responsibilities of the state when he entered Downing Street for the first time as PM in May 2010.
We hypothesized that BC would elevate BP in our cohort and that this PM component may in part explain the mixed results observed in the association between BP and PM2.5.
Alternatively, the composition of PM in different seasons may account for the different toxicity (Clarke et al. 1999; Huang et al. 2003a; Obot et al. 2002).
A rat inhalation study suggested that exposure to metal ions in PM may cause oxidative stress in the lung, leading to the production and release of proinflammatory cytokines and endothelin-1 into the circulatory system (Thomson et al. 2005).
A new report in the October 2007 issue of the Journal of Clinical Investigation shows that the increase in cardiovascular events seen after spikes in PM pollution may be due to macrophages in the irritated lungs producing increased amounts of interleukin-6 (IL-6), a cytokine that promotes clotting.
Bone marrow is a highly vascular tissue, so blood-borne toxicants in PM may continue to expose hematopoietic stem cells in the marrow, thereby promoting a positive feedback loop that establishes persistent methylomic alterations in the blood.
The accuracy of PMMR in determining PM interval may be useful in cases in which the time interval since death is unknown, such as delayed presentation and forensic cases.
Components in PM may induce different cardioregulatory responses, and a single component may induce different responses during different phases.
As theorized by Hartwig et al. (2002), metals such as nickel in PM may inhibit DNA repair enzymes.
One possible reason was, as noted previously, that the RM component involved in PM tasks may differ from the traditional retrospective memory tasks in terms of the extent of contextual cognitive support [ 31].
These pathophysiologic reactions in response to PM exposures may result in impaired fetal growth.
