Exact(12)
However, the results for the confounding effects on PM associations by including CO are different (but PM was not monitored in every city here).
The causal components driving the PM associations remain to be identified.
There was no significant confounding of the PM associations by CO or NO2 found in NMMAPS.
PM associations with airway inflammation in asthmatics may be missed using ambient particle mass, which may not sufficiently represent causal pollutant components from fossil fuel combustion.
However, seasonal patterns of PM associations with these outcomes are not consistent, and PM components responsible for these associations have not been determined.
The causal components driving the PM associations remain to be identified, but emerging evidence on particle size and chemistry has led to some clues.
Similar(48)
Mutation of the N-terminal Golli myristoylation site, required for PM association, abolishes its ability to regulate Ca2+ influx [ 24].
Interestingly, a fraction of Golli-BG21 is constitutively localized to lipid rafts at the PM and this PM association increases following T-cell stimulation [ 24].
In summary, our data on the G-domain mutants showed that ATP binding was required for PM association of EHD2 and for the formation of 60 75S complexes.
A possible explanation was that mixed or mutant EHD2 dimers could not form 60 75S complexes with mixed or mutant dimers, and were thus defective in PM association and oligomer formation.
The difference in τ stems from the difference in surface area of the RE in relation to the PM, which determines the rate of RE-dissociation and PM-association.
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