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Differentially expressed genes selection methods often focus only on the size of the single genes and the relationship of individual genes and disease, ignoring a plurality of pathogenic genes of the complex disease as a gene module with disease related, as well as within the module gene [ 7].
Individual gene expression value change is able to indicate the possible relation between this gene and disease but cannot identify the interaction between different genes and the plurality of pathogenic genes as a functional module in the complex disease [ 33, 34].
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CEO of Professional Science Editing for Scientists @ prosciediting.com