However the PI3K signalling pathway can also direct a plethora of other cellular functions and responses by the regulation of multiple transcription factors that includes FOXO [ 16, 31], p53 [ 32], YAP [ 33], NFkB [ 34], CREB [ 35, 36], c-MYC [ 37, 38], and c-JUN [ 39].
The PI3-kinase-Akt pathway, the major mediator of cell survival and a plethora of other key cellular functions, is the most common pathway deregulated in many cancers (Grant, 2008; Kinkade et al, 2008), including prostate cancer (Schmitz et al, 2007).
However, such features are likely to be more general features of chromatin states, and the principles seen in these examples are likely to be applicable to the plethora of other chromatin modifications whose function is still unclear.
Hence, Gene Ontology terms, describing the elements and their function, as well as identifiers for a plethora of other databases for genes, proteins, interactions, structural information, small molecules, etc. are added to the model.
But many others are pointing out a plethora of other options that Coag should consider.
The differences over Iran coincide with a plethora of other disputes.
These two government-supported databases served as models for a plethora of other databases.
We're also conserving Chinese forest, where there is a whole plethora of other things".
Simon makes his own sausages, pies, ready-made meals and a plethora of other delicacies.
Less mysterious is the plethora of other four-legged creatures that inhabit the wood.
