Sentence examples for plethora of mutations from inspiring English sources

In recent years, a plethora of mutations have been discovered in chromatin modifier genes.

Intriguingly, a number of neoplasms are defined by a plethora of mutations in epigenetic regulators, including renal, bladder, and adenoid cystic carcinomas.

One key lesson derived from these studies, owing to the simultaneous detection of the whole plethora of mutations in cells, is the cancer genome evolution.

Identifying the plethora of mutations responsible for complex I deficiency is challenging but essential for providing accurate and helpful diagnostic counselling.

However, full BRCA1 and BRCA2 screening still remains a tedious task due to gene length, the plethora of mutations, the high frequency of BRCA1 rearrangements requiring special technical approach, and mutation spectrum differences in different populations.

An alternative explanation is that the tumor risk is not significantly increased, e.g., because a plethora of mutations elsewhere in the genome contribute to tumor development in the reported tumors with SWI/SNF mutations.

Genetic analyses over the past two decades have connected a plethora of rare mutations with the risk for autism spectrum disorder (ASD) (1– 9).

The plethora of genetic mutations in epigenetic regulators in FL shown in this study therefore offers a compelling model disease to strategically test epigenetically-targeted therapies.

Nonetheless, a plethora of pathogenic mutations have been described to date in the seven mitochondrial-encoded subunits of complex I as well as in 12 of the nuclear-encoded subunits and in six assembly factors.

The plethora of human mutations that selectively impair different components of the phototransduction cascade [ 40– 43], combined with our ability to track the behavior of individual rods (and cones) over time, provides a unique opportunity to dissect, in vivo, the origin of these optical phenomena.

A plethora of A-domain mutations has been produced for XylR and DmpR (Text S1), which highlighted several residues in activation function.