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Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown.
In particular, the plethora of functional data can provide important regions on the protein that could conceivably be exploited as inhibitor targets.
The renewed interest in these organisms as cell factories stems from their unique and extensive metabolic assembly, which offers the possibility for the efficient biosynthesis of a plethora of functional biomolecules including vitamins, antimicrobials, conjugated linoleic acid, and trehalose.
The plethora of functional protein interactions of p53 at present precludes a clear understanding of regulatory principles in the p53 signaling network.
We discovered a plethora of functional Notch opa variants by sampling the Raleigh lines (DGRP) and genotyping multiple independent clones from each line by Sanger sequencing.
A plethora of functional and structural parameters were measured in 49 plant species following different growth strategies from five sampling sites located in Greece and Australia.
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By making use of reverse genetics approaches such as the one used in this study, a plethora of industrially functional products await discovery, not only in Ceratocystis but all of the thousands of fungi whose genomes are currently being sequenced (e.g. http://1000.fungalgenomes.org).org
Biological motor proteins have evolved a plethora of functionalities.
Furthermore, the isolation of antibodies directed against antigens of importance in health, disease and developmental processes, has yielded a plethora of structural and functional insights.
See related commentary by Zahed and Gupta, Traumatic brain injury (TBI) induces a plethora of structural and functional alterations, which contribute to subsequent deterioration as observed under clinical and experimental conditions.
In discussing our findings in context with other studies of CLC proteins, we largely reference the plethora of structural and functional studies of CLC-ec1, a voltage-independent 2Cl−/1H+ exchanger (6), and the voltage-gated Cl− channel CLC-0, which has gating that is sensitive to Cl− and H+ through the ancestral remnants of transport activity (12).
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