Sentence examples for plethora of changes in from inspiring English sources

Listeria's hemolysin, listeriolysin O (LLO) is an extremely potent virulence factor, which triggers vacuolar escape of the bacterium as well as a plethora of changes in the host cell (Hamon et al., 2012).

The increase in AVP biosynthesis in MCNs that follows osmotic stimulation is accompanied by a plethora of changes in gene expression (Mutsuga et al., 2004; Hindmarch et al., 2006; Yue et al., 2006).

However, senescent cells remain metabolically active and undergo a plethora of changes in protein expression and the secretion of cytokines and other factors involved in the senescence-associated secretory phenotype (SASP).

Moreover, a plethora of other changes in gene expression in the ependymal cell layer that might also impact upon hypothalamic structure have been identified, including decreased expression of nestin and the melatonin-related receptor GPR50 in Siberian hamsters in short days (Barrett et al., 2006).

Some of the most interesting questions to emerge from the present work relate to the possible mechanisms underlying the plethora of changes which have been identified in opioid dependence as cardiovascular risk factors, as potentially atherogenic processes and as accelerants of ageing processes.

Amid a plethora of changes, Ulster's performance became ragged in the closing stages with the Scarlets, boosted by scrum domination, added a further try with replacement Timani supplying the finish.

Although studies to date have revealed a plethora of genetic changes in hPSCs, the true extent of genetic variation in hPSCs is only likely to become apparent when we embark on whole genome sequence analysis.

In addition to its cytocidal effects, ionizing radiation has recently been shown to cause a plethora of changes on both the cancer cells and tumor stroma, critical in determining its therapeutic success.

This change in the balance of D1R and D2R signaling is only one of a plethora of changes that have been shown to occur during repeated drug use.

But the plethora of changes meant the game lost any meaningful pattern after half-time.

Among the plethora of changes observed at metamorphosis is the terminal differentiation of neurons, which, until that stage, have remained dormant since the time they arose in embryonic or larval neurogenesis.