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Contact guidance of neurites by topographic features is well known, but the role that topography plays in the modulation of neuritogenesis has not been addressed.
Perhaps the best example of the critical role HbF plays in the modulation of sickle cell anemia comes from the interaction of gene deletion HPFH with the HbS gene.
This association of VRK2 expression to a better prognosis in malignant astrocytomas is likely to be associated to the roles that VRK2 plays in the modulation of mitogenic, stress or apoptosis signaling [ 29- 32].
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This study not only demonstrates the importance of obtaining a comprehensive knowledge of ion channel expression and function in order to understand neuronal activity on a macroscopic level, but also underscores the complex and varied role that trace metals play in the modulation of sensory transmission.
mRNA secondary structures can play roles in the modulation of splicing, for example, by hiding or revealing splice sites and other regulatory elements or by modifying the spatial distance between cis-acting elements.
That HCRT plays a role in the modulation of trigeminal pain processing is supported by four lines of evidence: 1.
Our data strongly suggests that Spastin plays important functions in the modulation of cell membrane domains including the apical domains of photoreceptors during pupal eye development.
PTEN also plays a role in the modulation of the response to cetuximab.
It suggests that endostatin plays a role in the modulation of TBI independent of VEGF.
This suggests that p65 plays a role in the modulation of Nrf2 expression.
Taken together, our results suggest that xCT plays a role in the modulation of hippocampal long-term plasticity.
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