Sentence examples for play downstream from inspiring English sources

The iPhone X, indeed, is not a play downstream — instead, it is a play going even further upstream and providing a more premium product.

In an effort to begin to elucidate the molecular mechanisms at play downstream of ephrinB2 over-expression, RT-PCR was performed on the GAMs which revealed no significant changes in runx2 or BMP2 expression but an upregulation of osterix (Osx) and Dlx5 expression prompting the belief that the mode of osteogenesis is independent of the BMP2 pathway.

The roles that these proteins play downstream of TORC1 are discussed below.

The roles that these gene products play downstream of TGF-β during tumorigenesis have not been extensively studied [ 14, 15].

The role that such variability may play in downstream disease risk and morbidity deserves further study.

Thus, Bim does not appear to play a downstream role in promoting death of Mcl-1-deficient thymocytes.

However, Asrij does not play a downstream role in the JAK-STAT pathway in maintaining the HSC population, as stat92e depletion in lymph glands along with forced expression of Asrij leads to precocious hemocyte differentiation, thereby disrupting hemocyte homeostasis.

We found that dominant-negative Rac1 and constitutively-active RhoA reversed the effect of Dvl2 on SG assembly, suggesting that Rac1 and RhoA play a downstream role (Fig. 2C,D).

BNIP1, APOBEC3F and LDOC1 are such genes consistently identified in our models, suggesting that induction of apoptosis, innate immune response and cell-proliferation regulation may play important downstream roles in development of hypertension.

To elucidate the mechanisms by which IL-1β upregulates L-PGDS expression, we evaluated the roles played by downstream signalling cascades using specific pharmacological inhibitors.

To gain further insights into the mechanism by which leptin, together with IL-1, promotes NO production, we evaluated the roles played by downstream signalling cascades using specific pharmacological inhibitors.