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These findings demonstrate that during normal aging the prostate stroma exhibits phenotypic and molecular characteristics plausibly contributing to the striking age associated pathologies affecting the prostate.
In addition, myofibroblast contraction activates latent endogenous TGF-β1 stores on the ECM [ 35], thereby plausibly contributing to myofibroblast maintenance.
A set of loci plausibly contributing to the observed excess of ancestral haplotypes among major haplotypes include CDC25A, CDKN2A, and SMAD4.
Whether this is a cause or effect is still unclear, with hypogonadism-induced obesity and obesity-induced androgen deficiency both plausibly contributing to a bidirectional effect on disease pathology.
One gene (hadA at BPF-specific locus 10) has recently been characterized as encoding an epithelial adhesin/invasin plausibly contributing to HaeBPF virulence (36 ), but the function of the others, and any part their products may play in the serum resistance of the HaeBPF clone that endows it with pathogenic potential, remains to be established.
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A number of studies have addressed factors that plausibly contributed to child mortality in Tanzania.
While the representational or epistemic features of an aesthetic experience might very plausibly contribute to its value, such features very implausibly contribute to the value of the object affording such an experience.
Friendship is a good that plausibly contributes to the objective value of human lives, but if states try to promote it directly they may do more harm than good.
"True polar wander could plausibly contribute to sea-level changes," he says, "but the effect ranges from 10 meters to 150 meters depending on our assumptions of what Earth is made of".
Equally plausible, however, is the emerging hypothesis that participants with short LTL in our study had the greatest proportion of accumulated senescent bodily cells overall, including fibroblasts and epithelial cells, which could plausibly contribute to the observed higher levels of IL-6 and TNF-α in this group [28], [38].
Thus enhanced ephrin signaling plausibly contributes to tumor suppression by TGF-β in ER+ breast cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com