Nevertheless, such a causal link is biologically plausible because sleep loss may lead to metabolic abnormalities and weight gain through the regulation of hypothalamic-pituitary-adrenal axis [ 47, 48].
It is plausible that sleep duration varies across the week and during the day (eg, naps), particularly between weekdays and weekends, but the measure of sleep available in the 45 and Up Study was generalist and could not facilitate these more detailed enquiries.
ICU delirium is a risk factor with a plausible link to sleep disturbance and disability.
"It is plausible, therefore, that sleep fragmentation may be a link between loneliness and downstream health outcomes," the authors wrote.
It is also plausible that healthier sleep durations promoted by exposure to green space may aid mental health and participation in physical activity.
It is plausible that abnormal sleep patterns may increase the risk of visual impairment by affecting systemic and ocular blood supplies, but additional research studies are necessary.
Such associations are plausible, given that sleep requirements change markedly in early adolescence at the same time as puberty, and that melatonin, a pineal hormone, which is one of the key physiological regulators of the sleep cycle, changes with puberty in healthy humans [ 44].
If you're in a bad mood, you're more likely to blame plausible causes, such as sleep quality, for the difficulty you're facing.
Dysfunction of the locus subcoeruleus is therefore considered as the plausible cause of REM sleep without atonia in patients with Parkinson's disease with RBD.
This is clinically plausible because alterations in sleep duration may represent normal physiological changes attributable to pregnancy while exhaustion may be a stronger indicator of sleep insufficiency resulting in compromised daytime functioning.
