As has been well established, however, drawing a plausible wiring diagram for a rhythmic circuit does not allow the immediate inference of actual circuit activity patterns [17].
Here we show how biologically plausible processing motifs in neural circuits could be tuned to extract this information.
Distributed dendritic inhibition of retinotopic elements as implemented in our Indirect Distributed Inhibition model is the most plausible wiring scheme for the neuronal circuit of FD-cells.
To address the observed heterogeneity in NANOG expression levels, we also explore a biologically plausible scenario to couple the core circuit to extracellular signals.
Our findings place TMEM135 among the plausible candidate genes involved in our hypothesized feedback regulatory circuit, a circuit critical to enhancing the rate of survival in fatty acid oxidation-deficient mice.
Computing an inverse model from a forward model is a technique used for industrial plant control [33] and has already been applied to motor control [12], [34], however, the proposed circuits were hardly biological plausible.
Integrating the above findings, it is plausible that development/function of language-related circuits in the human brain could be disturbed by imbalances in relative functional dosage of FOXP2 and FOXP1.
In 1872 Ludimar Herman had suggested an ingenious and highly plausible explanation that became known as the local circuit hypothesis.
