Sentence examples for platinum plasma from inspiring English sources

Total platinum plasma levels which were determined daily showed highly elevated values (2.9 mg platinum per kg plasma).

For the analysis of total platinum, intact cisplatin, monohydrated cisplatin and unbound platinum, plasma samples were collected just before treatment and at 0.5, 1, 1.5, 2, 3, 4 and 6 h after the start of the cisplatin infusion.

Total platinum in plasma and unbound platinum in deproteinised plasma were measured by flameless atomic absorption spectrometry (FAAS) (Verschraagen et al, 2003a).

Pharmacokinetics of the two compounds administered i.v. at equitoxic dose levels to tumor-bearing mice indicated similar decay kinetics of total platinum in plasma, kidney and the tumor.

The secondary target was the AUC of unbound platinum in plasma.

The exposure to cisplatin was defined by DNA adducts in WBC and AUC of unbound platinum in plasma.

Concentrations of total platinum in plasma and tissue homogenate were quantitated by atomic absorption spectrophotometry (AAS) as described previously [ 28].

Proteins associated with the transport of platinum through plasma membranes and genes associated with cisplatin resistance appear to be close to being elucidated.

Elemental platinum in plasma and ultrafiltrate was determined by flameless atomic absorption spectrometry using a modification of a procedure described by Kloft et al (1999a).

The oxidative renal injury is both dose-dependent and time-dependent, as evidenced by renal anti-oxidant depletion, enhanced lipid peroxidation, platinum content, plasma creatinine BUN, and blood urea levels in rat models [ 8].

A single dose of amifostine increased the AUC (area under the curve) values of total platinum in plasma ultrafiltrate (30.1 vs 18.2 microM x h), liver (307.7 vs 236.4 nmol g -1) x h), kidney (500.8 vs 368.3 nmol g -1) x h) and OVCAR-3 tumour tissue (184.0 vs 146.8 nmol g(-1) x h).