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Patients with recurrent ovarian cancer with > 6 months of platinum free interval were considered eligible.
However, platinum-based treatment is associated with significant toxicities, therefore development of alternative platinum free chemotherapy combinations are warranted.
All patients had received 1 3 lines of previous chemotherapy and had a minimum platinum free interval of 6 months.
Patient relapsed after 23 months of platinum free interval with numerous tumor implants in intra- and extra-pelvic peritoneum (Fig. 1a).
As well as the definitions of platinum-sensitive disease being different (platinum-free intervals of 12 and 6 months respectively), in the study by Meyer et al (2001) platinum-sensitive patients had received more prior chemotherapy (2.63 courses compared to 1.13) and had a shorter platinum free interval (10.5 months vs 25 months).
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Acal's systems are powered by its proprietary platinum-free cathode technology (FlowCath).
Asazawa, K. et al. A platinum-free zero-carbon-emission easy fuelling direct hydrazine fuel cell for vehicles.
Creation of cost-effective and platinum-free counter electrodes (CEs) is persistent for developing advanced dye-sensitized solar cells (DSSCs).
Decreasing this cost depends on finding a durable cost-effective platinum-free electrocatalyst.
Fong, P. C. et al. Poly(ADP -ribose polymerADP -riboseion: frequent durable respolymeraseBRCA carrinhibitionn cancer correlating with platinum-frequenterval.
Ask the company how things are going with its platinum-free converters now, and the response is a copy of the 1988 press release.
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