"The neighbourhood has a historic feeling – the sense that there are multiple histories that all contributed to the neighbourhood fabric – and that feeling is going away," says Bobby LeFebre, creator of the website We Are North Denver, a platform for creative responses to gentrification.
This approach also provides a general platform for programmed responses to other complex cell states.
The Office of the United States Global AIDS Coordinator in the Department of State claims that PEPFAR is, "moving from its initial emergency focus to a heightened emphasis on sustainability, and serving as a platform for expanded responses to a broader range of global health needs".
The suitability of MEA platforms for measuring drug responses of hESC-CMs has been shown in 2D culture [ 28, 43, 44].
Research and public health interventions must be anchored in the policy, health system, and community platforms for a holistic response.
Deans at Columbia Engineering and Mailman sponsored a rapid-fire design challenge that quickly yielded several products that could aid in the fight: a mobile platform for rapid response, patient care and data tracking; an Ebola-specific containment suit; and a blue-bleach solution to aid decontamination.
Whilst some countries have considered utilising decentralised infrastructures, centralised systems remain the dominant platform for pandemic response strategies.
There are worldwide steps that industry groups and government can take together to make supply chains more resilient, such as institutionalizing a risk assessment process within a broad-based, neutral international body, or expanding the use of data-sharing platforms for risk identification and response.
Military and emergency response platforms, for example, have protocols and processes for publishing updates to the situation awareness database and subscribing to particular types of information, such as new events occurring in a geographic area (DeMarco, 2016; Liang and Gao, 2010).
Finally, we show that PDX, derived from the therapy-resistant metastases, can display similar pleiotropy in resistance mechanisms, making PDX a valuable experimental platform for studying drug responses.
