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We have provided some circumstantial evidence and speculative discussion in support of the idea that DivIVA-mediated polar growth could have provided the platform for the evolution of mycelial growth and that actinobacteria-specific features of cell division may have contributed to the specialised processes by which aerial hyphae form chains of spores.
The phylogenetic-structure of the metabolic network, which is described here for the first time, emphasizes the gradual evolution of processes which are specific to a tissue, whereas the development of a phenotype in an ancient lineage provides a platform for the evolution of more recent traits.
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Moreover, these clones frequently harbour well-adapted plasmids maintained by selection-transfer balance, which might disseminate AbR among genetic exchange communities, even in the absence of antibiotic exposure, serving as raw platforms for the evolution of novel beneficial functions (Boon et al. 2014; Knöppel et al. 2014).
In this issue of Chemistry & Biology, Kintses and coworkers describe a microfluidic platform for the directed evolution of enzymes in droplets that allows for the screening of 107 mutants per round of evolution.
We have recently developed a screening platform for the directed evolution of artificial metalloenzymes based on the streptavidin biotin technology in the periplasm of the Gram-negative bacterium Escherichia coli.
We also provide results demonstrating the use of yeast as a platform for the development of combination therapeutic strategies designed to prevent the evolution of anticancer drug resistance.
The environment change would globalize and stabilize the effect of the Nrr, casting a firm DNA-genome platform for the long-term evolution (Fig. 2d).
Furthermore, because the genome provides the platform for evolution, insights from genomics should yield insights to evolution.
Daphnia pulex (water flea), crustacean represents a particularly useful platform for the study of SSR evolution.
Thus, in the light of our results, we believe that our assay, besides enabling protease substrate profiling, also may serve as a highly competitive platform for directed evolution of proteases and their substrates.
We first emphasize that Avida is a widely used platform for studying evolution.
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