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Platform entry was less in DMSO Tg-APP (76%) compared to WT (Fig 6E, full bars) and Bosutinib significantly increased platform entry (6.2-fold) compared to DMSO Tg-APP mice (Fig 6E, p = 0.03, N = 12).
Main distance was not changed in parkin−/− ± Bosutinib compared to control, suggesting that the changes in platform entry are not attributable to less movement in parkin−/− mice.
All parameters, including distance travelled to reach platform, speed to get to the platform, latency or time spent on platform and platform entry were digitally recorded on a computer and analysed by a blind investigator.
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Times spent on open arms, closed arms and central platform, entries into open and closed arms were scored.
Mean frequencies of each behavioral element showed in DA/Han strain a value significantly lower than in Wistar for central-platform entry, open arm-entry and closed-arm entry and a significant higher value for central- platform sniffing, open-arm sniffing and corner-rearing.
Elan's chief executive identified Liposome as a platform for entry into the oncology area; the two companies share an expertise in drug delivery systems.
Despite this progress, clinical features still serve as the platform for entry into clinical trials of novel agents.
As the Regional Lead for M&A and Investments, she led investments into banks and developed the banking platform's entry into seven countries in Africa.
To track sample identity, 30 single nucleotide polymorphisms (SNPs) including sex chromosome markers were typed on the Sequenom platform before entry to the whole genome genotyping pipeline.
At the busy Friedrichstrasse station in Berlin, where national, regional and commuter train lines intersect, heavily armed officers in dark uniforms patrolled the platforms and entry and exit points during the afternoon rush.
AfterCollege, a platform supporting entry-level jobs and internships for recent college grads, just acquired CollegeFeed, a social network for job-seeking college students started by a former Googler.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com