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Ultrasonic vibration is widely utilized in manufacturing processes mainly because acoustic field could significantly affect the metal plasticity leading to stress reduction.
Significant fibre rotations take place, permitted by matrix plasticity, leading to a post-yield stiffening of the laminate, as the fibres reorient towards the direction of loading.
But as you get older, the brain can lose some of this plasticity, leading to a longer withdrawal".
The tPA/PAI-1 system in astrocytes by promoting brain plasticity leading to functional recovery after treatment of stroke with MSCs may provide a new therapeutic target for stroke and CNS diseases.
These processes would be explained, at the cellular level, by the leptin-mediated modulation of hippocampal synaptic plasticity, leading to the conversion of hippocampal short-term potentiation (STP) into LTP, via enhancing NMDA receptor function [55].
Given the role of mitochondria in decreased metabolism and increased generation of ROS with aging, there is a strong a priori argument that mtDNA variation may contribute to global losses in metabolic plasticity leading to the decreased resilience that is a hallmark of the frailty phenotype.
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Thus, functional or metabolic alterations in DS astrocytes may affect normal spine development and plasticity, ultimately leading to abnormal synapse and circuit formation.
It is, therefore, likely that this decrease in spine number results in altered synaptic plasticity, possibly leading to decreased parallel fiber connectivity.
In addition, it has also been suggested that the inhibitory system could filter the activity of the deprived eye inputs favouring plasticity processes leading to their functional disconnection [5], [39].
Persistent high-level expression of TNF α and IL-1 β is important to the progressive degeneration of neuronal connectivity and loss of neuronal plasticity ultimately leading to cognitive decline.
Despite the requirement for Tau in multiple aspects of A β-induced neurotoxicity, a large knowledge gap exists as to how the A β oligomer-induced neurotoxic signals are transduced intracellularly to impair synaptic plasticity, eventually leading to neurodegeneration.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com