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Before thawing, 3.2% citrate solution was added in a 1 9 solution:plasma ratio.
Despite having a larger tumor to plasma ratio (Table 2), nanosuspension delivery resulted in less anti-tumor efficacy (Figure 6).
In particular, the liver to plasma ratio was exceptionally high being approximately 225-fold higher with nanosuspension delivery.
Despite a higher tumor to plasma ratio for the nanosuspension treatment group, absolute paclitaxel tumor exposure was higher for the USP group.
However, both Ins isomers can be positively associated in the management of PCOS patients in a ratio corresponding to their physiological plasma ratio (40 1).
Permeability, in terms of the lavage fluid to plasma ratio of fluorescence-labelled albumin, was significantly enhanced by CO inhalation (fig. 9C).
Similar(33)
The average tissue-to-plasma ratio was shown in Figure 2.
Figure 2 Tissue-to-plasma ratio curve averaged across subjects ( n = 4) in six ROIs.
Similarly, alteration in renal elimination resulted in increased brain distribution (brain-to-plasma ratio: 10.98 vs. 6.88).
Lithium accumulation into the brain was more marked in the presence of previous chronic exposure (brain-to-plasma ratio at 54h: 131.27 vs. 6.42; p< 0.0001).
Co-administration of probenecid increased the brain-to-plasma ratio of BSP and PHT in the brain of both normal and PTZ-kindled rats.
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