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In quantitative evaluation, pharmacokinetic modeling is performed using two compartment models that determine Ktrans (forward volume transfer constant) and kep (reverse reflux rate constant between extracellular space and plasma) rate constants [ 34].
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The interstitium-to-plasma rate constant (kep), extracted from dynamic contrast enhancement (DCE-MRI) MRI data, seems to have an important role in the assessment of patients with brain tumors.
Three studies [ 20– 22] used the ICG plasma disappearance rate or retention rate at 15 min [ 56].
The indocyanine green plasma disappearance rate (0.103) and 15-min retention rate (23.9%) suggested depressed liver function.
After nutritional therapy, the indocyanine green plasma disappearance rate (0.150) and 15-min retention rate (11.9%) were recovered.
The oxygen plasma etching rate of PMMA nanochannels was studied, and the average rate was 15 nm/min under optimal conditions.
Because of this, the plasma flow rate through the liver took up a larger percent of the total plasma flow rate represented in the model.
plasma disappearance rate.
indocyanine green plasma disappearance rate.
plasma disappearance rate of indocyanine green.
The plasma clearance rate of indocyanine green was 0.224.
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