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An additional venous blood sample was taken before 11C-TMSX administration, which was used for the in vitro assessment of the fraction of 11C-TMSX in plasma bound to plasma proteins (fP).
A technique for the kinetic simulation of plasma flow in strong external magnetic fields was developed which captures the compression and expansion of plasma bound to a magnetic flux tube as well as forces on magnetized particles within the flux tube.
Similarly, in humans, most cortisol is found in the plasma, bound to CBG [9].
The drug is distributed to different components of the blood, namely, dissolved in the plasma, bound to plasma proteins (namely, albumin) and, as we established with this study, bound to cell membranes.
It hydrolyses lipid peroxides, and circulates in plasma bound to high-density lipoproteins (HDL) [ 4].
Both PR8-immune mouse sera and lamprey plasma bound NP better than unimmunized control.
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Indeed, approximately 60% of nevirapine in plasma is bound to plasma proteins and the free fraction of nevirapine could drive significant quantities of nevirapine into saliva and other matrices.
The compound was highly plasma protein bound to human plasma proteins (>99%), though it was somewhat less tightly bound to mouse plasma proteins (∼84%).
Oxygen in the blood plasma binds to haemoglobin present in the red blood cells.
HIV and HCV antibodies in serum or plasma bind to antigens in the sol-gel spots (Step 1).
DOI: http://dx.doi.org/10.7554/eLife.07467.007 10.7554/eLiFigure67.008 Figure 3 figure supplement 3. PR8 immunized lamprey plasma binds purified NP protein, but not purified M1 by ELISA.
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