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Recently, scientists have found the resemblance between psoriasis plaques and atherosclerosis plaques structure.
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We concluded that Tg2576 and APPswe-PS1dE9 mouse models are not suited to small animal imaging studies with tracers that shared binding sites with [11C]PIB and [ 18 F]flutemetamol, due to their plaque structure or low plaque load.
At a resolution of 8 16 mm for whole body scans PET alone is unable to reveal plaque structure but will primarily give general localization[36].
Despite descriptions of initial plaque formation on the tooth surface, studies on mature plaque and plaque structure below the gum are limited to landmark studies from the 1970s, without appreciating the breadth of microbial diversity in the plaque.
Therefore, biomechanical analysis may provide complementary information to plaque structure and luminal stenosis in determining vulnerability.
11β-HSD1 inhibitior or deficiency attenuated atherosclerosis (74 76%) without deleterious effects on plaque structure.
Ultrasonic plaque structure was defined according to the classification proposed by Gray-Weale et al. (1988).
Activated DCs regulate effector T cells which can kill plaque-resident cells and damage the plaque structure.
Being embedded in the atherosclerotic plaque, neovessels are also presumably susceptible to mechanical loading effects from the deformation of entire plaque structure driven by the dynamic blood pressure.
In addition, it may be that the plaque structure would not be maintained if the lipids most tightly associated with the channels were removed.
For connexin channels this is no doubt true; lipids are likely to have modulatory influences and play fundamental roles in junctional plaque structure and/or maintenance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com