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We concluded that Tg2576 and APPswe-PS1dE9 mouse models are not suited to small animal imaging studies with tracers that shared binding sites with [11C]PIB and [ 18 F]flutemetamol, due to their plaque structure or low plaque load.
At a resolution of 8 16 mm for whole body scans PET alone is unable to reveal plaque structure but will primarily give general localization[36].
Despite descriptions of initial plaque formation on the tooth surface, studies on mature plaque and plaque structure below the gum are limited to landmark studies from the 1970s, without appreciating the breadth of microbial diversity in the plaque.
Therefore, biomechanical analysis may provide complementary information to plaque structure and luminal stenosis in determining vulnerability.
11β-HSD1 inhibitior or deficiency attenuated atherosclerosis (74 76%) without deleterious effects on plaque structure.
Ultrasonic plaque structure was defined according to the classification proposed by Gray-Weale et al. (1988).
Similar(37)
Standardised definitions of focal plaque structures such as luminal encroachment of 50% or >0.5 mm should be adopted to help differentiate the two distinct diseases processes [ 18].
The differences in the phospholipid species found uniquely in Cx26 and Cx32 plaques suggest that the integrity of plaque structures formed by these two connexins have distinct phospholipid requirements.
Disc Large protein is a component of the septate junctions in Drosophila epithelial cells, a part of the neuromuscular junction bouton, and the internalized plaque structures appear to be distinct from these previously identified subcellular localizations [ 51, 52].
To exclude the possibility that these 'flower' clusters were not simply an artifact caused by Methoxy-XO4, we stained age-matched naïve mice that did not receive Methoxy-XO4 prior to post-mortem staining and observed identical flower plaque structures (Suppl. Fig. 4a c).
Recently, scientists have found the resemblance between psoriasis plaques and atherosclerosis plaques structure.
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