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This study examines tumor movements to design individualized margins to account for these movements and evaluates their dosimetric impacts on planning volume.
In proton therapy, passive scattered proton plans use compensators to conform the dose to the distal surface of the planning volume.
The homogeneity of the dose within the planning volume was within ±10% of the prescribed dose.
With respect to planning volume definitions and dosimetric parameters, the Phase II hemigland brachytherapy protocol defines the gross target volume as the visible disease on preoperative MRI that can be fused to the intraoperative ultrasound images.
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The planning volumes are then overlaid on the ultrasound images and adjusted until they match.
The concordance index of cone beam CT treatment volumes compared with planning volumes was calculated and displacements measured.
The correct designation and contouring of the planning volumes are ultimately the responsibility of the radiation oncologist.
It had to be midsized -- small enough so an extra $500,000 in annual income would make a difference, yet large enough to handle the planned volume.
In the past few years, new 3-dimensional dose-calculation algorithms have been generated that more accurately calculate dose distributions throughout the treatment-planning volume.
That's three times as much as it planned volume.
* PTV-1, planning target volume of gross tumor; PTV-2, planning target volume of clinical target volume; PTV-3, planning target volume of bilateral supraclavicular fossa.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com