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HHL and JH conceived the study and participated in its design and the planning of analyses.
YL and XH participated in planning of analyses and revising the manuscript.
JGJ, TAH, IL and VPH contributed to planning of analyses and interpretation of results.
KM contributed to the conception and design of the study, planning of analyses, and drafted the manuscript.
ARG contributed to study design and planning of analyses, analysed the data and revised the draft paper.
The planning of analyses and interpretation of the data was the joint product of discussions between MCW and HS.
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The initial plan of analysing qualitative comments using thematic analysis was therefore abandoned.
This also has important implications for the design and conduct of clinical trials, such as the planning of interim analyses.
SL was involved with the planning of the analyses and in the thinking that resulted in Table 1.
Sixthly, included protocols were approved 10-13 years ago; the planning of subgroup analyses in protocols may have improved since that time.
S.H., M.C., M.B. (Beynon), L.R., S.N., A.S., M.B., C.H., M.K. and J.F. contributed to planning of the analyses.
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CEO of Professional Science Editing for Scientists @ prosciediting.com