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Determination of the maximum tolerated dose (MTD) for NM-IL-12 is not planned in this study, rather, a pre-defined starting dose will be explored; this dose is based on two safety and tolerability studies of NM-IL-12 in healthy volunteers.
A sample size of 25 (no replicates per product on the pig) was planned in this study based on a power calculation.
Therefore, a conventional analysis of the secondary endpoints was not planned in this study.
Two rounds of visits are planned in this study too, each focusing on one topic.
Adverse effects are generally temporary and can be minimised by gradual dose escalation, as planned in this study.
However, compared to the topical application, which is planned in this study, much higher drug concentrations are used in systemic use of bevacizumab.
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Research of this type was planned in the study protocol, but was not included in the final publication.
Pregame's planning step corresponds to the release backlog and project planning activities in this study's solution.
Ten patients, who were partially edentulous in the mandibular posterior region for whom a single nonsubmerged implant was planned, participated in this study.
The managed care plan participating in this study, Harvard Pilgrim Health Care (HPHC), is the largest HMO in New England, and is a not-for profit entity.
We are interested in sea vessel type selection to efficient vessel fleet planning in this study.
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CEO of Professional Science Editing for Scientists @ prosciediting.com